University faculty and outreach program directors have been called to deliver more effective, equitable, and sustainable ways in which neighborhood and university communities may creatively interact. The authors report on the case of the Pittsburgh Studio, an initiative that matches students and resident stakeholders in researching local issues and identifying place-based solutions to catalyze resilience and conviviality in low-income neighborhoods. This article traces the cooperation of the Pittsburgh Studio and the Penn State Center, describes its conceptual basis, and concludes by outlining emerging best practices for neighborhood-based engaged scholarship in the post-industrial inner city.